一、基本信息
赵晓娟,女,1986年5月生,山西太原人,博士,讲师。2010年本科毕业于吉林农业大学动物医学系,获农学学士学位;2010/09-2012/12进入南京农业大学攻读临床兽医学硕士,主要从事中药脂质体免疫佐剂研究,获农学硕士学位;2013/07-2014/08年在江苏省农业科学院工作,主要从事兽用水/油/水型佐剂的研发;2014/09-2018/06年在南京大学攻读药学专业博士研究生,获理学博士学位;2018年9月年起进入盐城师范学院任教。
二、研究方向
药理学
三、开设课程与教学成果
现主要承担生物化学、医用材料学理论及药学基础实验(一)、生物医学信息分析实验、医用材料基础实验的教学工作。
四、科研项目与学术成果
主要研究方向是中药单体干预代谢性疾病效果及药理作用分子机制研究。已发表SCI科研论文6篇,参与国家自然科学基金3项。
代表性论文:
(1) Yan-Zi Yang#, Xiao-Juan Zhao#, Hong-Jiang Xu, Shan-Chun Wang, Ying Pan, Shui-Juan Wang, Qiang Xu, Rui-Qing Jiao, Hong-Mei Gu, Ling-Dong Kong*. Magnesium isoglycyrrhizinate ameliorates high fructose-induced liver fibrosis in rat by increasing miR-375-3p to suppress JAK2/STAT3 pathway and TGF-β1/Smad signaling, Acta Pharmacol Sin, 2018, [Epub ahead of print].
(2) Xiao-Juan Zhao, Han-Wen Yu, Yan-Zi Yang, Wen-Yuan Wu, Tian-Yu Chen, Ke-Ke Jia, Lin-Lin Kang, Rui-Qing Jiao, Ling-Dong Kong*. Polydatin prevents fructose-induced liver inflammation and lipid deposition through increasing miR-200a to regulate Keap1/Nrf2 pathway, Redox Biol, 2018, 18: 124-137.
(3) Xiao-Juan Zhao#, Yan-Zi Yang#, Yan-Jing Zheng, Shan-Chun Wang, Hong-Mei Gu, Ying Pan, Shui-Juan Wang, Hong-Jiang Xu, Ling-Dong Kong*. Magnesium isoglycyrrhizinate blocks fructose-induced hepatic NF-κB/NLRP3 inflammasome activation and lipid metabolism disorder, Eur J Pharmacol, 2017, 809: 141-150.
(4) Xiao-Juan Zhao, Yu Lu, Yang Tao, Ye-E Huang, De-Yun Wang*, Yuan-Liang Hu, Jia-Guo Liu, Yi Wu, Yun Yu, Cui Liu. Salidroside liposome formulation enhances the activity of dendritic cells and immune responses, Int Immunopharmacol, 2013, 17(4): 1134-1140.
(5) Xiao-Juan Zhao, Jia-Guo Liu, Yuan-Liang Hu, Yun-Peng Fan, De-Yun Wang*, Ju Yuan, Liu Xu, Liu Cui, Jing Zhang. Optimization on condition of glycyrrhetinic acid liposome by RSM and the research of its immunological activity. Int J Biol Macromol, 2012, 51(3): 299-304.
(6) Xiao-Juan Zhao, Yun-Peng Fan, Deyun Wang*, Yuanliang Hu, Li-Wei Guo, Shi-Liang Ruan, Jing Zhang, Ju Yuan. Immunological adjuvant efficacy of glycyrrhetinic acid liposome against Newcastle disease vaccine. Vaccine, 2011, 29(52): 9611-9617.
五、联系方式
通讯地址:盐城市希望大道南路2号盐城师范学院药学院
邮编:224007
联系电话:13770509560
E-mail:zhaoxiaojuan1986@126.com